Intercellular vs Follicular Delivery: How Products Actually Enter Skin

Intercellular vs Follicular Delivery: How Products Actually Enter Skin

Skin isn’t a flat wall — it’s a complex, multi-pathway system.
There are two primary routes topical products use to move into skin:

Intercellular delivery

  • Between skin cells
  • Influenced by viscosity and lipid compatibility

Follicular delivery

  • Via hair follicles and sebaceous units
  • Often deeper and more efficient for certain actives

Many traditional products rely almost entirely on intercellular movement, which can be slow and inconsistent. Low-viscosity micellar systems naturally take advantage of both routes.

Key takeaway: Dual-route delivery improves consistency, comfort, and performance.

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